Inactivation of prelimbic and infralimbic cortex respectively affects minimally-trained and extensively-trained goal-directed actions
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چکیده
منابع مشابه
Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction.
Rats were subjected to one or two cycles of context fear conditioning and extinction to study the roles of the prelimbic cortex (PL) and infralimbic cortex (IL) in learning and relearning to inhibit fear responses. Inactivation of the PL depressed fear responses across the first or second extinction but did not impair learning or relearning fear inhibition (experiment 1). Inactivation of the IL...
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BACKGROUND The medial prefrontal cortex has been implicated in a variety of cognitive and executive processes such as decision making and working memory. The medial prefrontal cortex of rodents consists of several areas including the prelimbic and infralimbic cortex that are thought to be involved in different aspects of cognitive performance. Despite the distinct roles in cognitive behavior th...
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Recent findings across a variety of domains reveal the benefits of self-produced experience on object exploration, object knowledge, attention, and action perception. The influence of active experience may be particularly important in infancy, when motor development is undergoing great changes. Despite the importance of self-produced experience, we know that infants and young children are event...
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The role of the intraparietal sulcus (IPS) in number processing is largely agreed on. A current debate however concerns the specificity of the involvement of the IPS in representing numbers or ordinal sequences more generally. To test this specificity, we investigated whether the IPS would be activated by extensive training on an arbitrary ordered sequence. We found that the hippocampal-angular...
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How motivation influences habitual behavior is unclear, since only motivational decrements have been considered. Here, in two experiments, we investigated the effects of motivational up-shifts and side-shifts on instrumental behavior which was extensively trained using a protocol known to promote habitual responding. In Experiment 1, hungry rats were trained to lever press for sucrose solution....
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ژورنال
عنوان ژورنال: Neurobiology of Learning and Memory
سال: 2018
ISSN: 1074-7427
DOI: 10.1016/j.nlm.2018.07.010